Kill Senator Muppy Doo - High on Life 2 Full Walkthrough & Boss Fight Tips (2026)

The eighth mission in High on Life 2 is a thrilling adventure, but it's not without its challenges. Prepare to attend a series of conventions, from PoliCon to MurderCon, and unlock a new Gatlian ally. But here's where it gets controversial—you're tasked with assassinating Senator Muppy Doo, a morally ambiguous mission that raises questions about the game's narrative choices.

Steal a Catalytic Converter for the RV:
The mission begins in the City Plaza, where you must retrieve a specific catalytic converter for your RV. Using your Info Scanner, locate it near the Krust Theatre and the Rhea Pharmaceutical building. Grab the required parts from a nearby auto shop, triggering an alarm and a brief skirmish with security.

Infiltrate ParkingCon and Find a Parking Spot:
Your next challenge is ParkingCon, where you must find a parking spot for Gene's RV. Clear out enemies and secure a spot, only to have it stolen. After a series of attempts, you'll need to escape ParkingCon and navigate through a medical area.

Get to PoliCon:
On your way to PoliCon, you'll encounter a malfunctioning tram. Wall ride a MurderCon billboard and grind railings to reach the convention. To enter PoliCon, you must take a service elevator, defying the operator's instructions and using Knifey to manipulate the elevator controls.

Find Hall H Using Lugblobs:
Inside PoliCon, you must find Hall H, where Senator Muppy Doo is speaking. Use Lugblobs to unlock the door by following orange slime trails. Be cautious of the Death Laser that will activate if you try to attack Muppy Doo directly.

Disable Hall H Security:
Before confronting Muppy Doo, you must disable the security system in Hall H. Find two Lugblobs and place them on Power Pads near the security system. Use Sweezy's Time Bubble ability to navigate spinning fans and rotating exhaust panels, then climb up hotwalls to reach the Lugblobs.

Tips for Fighting the Mysterious Alien:
Just as you're about to kill Muppy Doo, he escapes, and you're left fighting a mysterious alien who was also targeting the senator. This alien has fewer attacks than other bosses, but his burst fire and melee slashes can be deadly. Use floating metal balls with shield capsules to protect yourself.

Defeat the Security Guards and Chase Muppy Doo:
After defeating the alien, you gain a new weapon, Sheath, and must lower a large wall. Use Sheath's electric spike ability to connect power junctions and amplifiers. Then, face a group of security guards, using Sheath's accurate burst fire to your advantage.

Sign Up for MurderCon:
At MurderCon, sign up for a deadly competition. After signing a waiver, you'll find an upgrade for Sheath. The event begins in a foggy arena, where you must slay enemies and listen for the announcer's cues to earn double points. Stay alert for Brutus, the top competitor.

Tips for Fighting Brutus:
Brutus is a formidable opponent who uses a ball and chain. Parry his attacks with Knifey to stun him and target his vulnerable skull. Eliminate other competitors for shield capsules, and use walls for temporary cover. Brutus can grapple towards you, so be cautious when moving between floors.

Follow Muppy Doo to HumanCon:
After defeating Brutus, navigate through minor conventions to reach HumanCon. Use Sheath's electric spike to create a zipline, connecting junctions and metal balls. Solve a Lugblob puzzle, learning that Lugblobs can function as moveable junctions. Create a zipline to reach HumanCon.

Enter HumanCon and Find Muppy Doo:
To enter HumanCon, solve an electric spike puzzle to open the front door. Use Gus to vacuum a Lugblob and rotate block towers to create a linear connection. Once inside, trigger a cutscene and engage in a unique fight with Muppy Doo.

Tips for Fighting Senator Muppy Doo:
Muppy Doo is not a fighter and will keep running away. Defeat his summoned guards and chase him as he shrinks and flees. When you deplete his health bar, he escapes into his fanny pack. Pick it up to initiate the second phase of the battle.

Fighting Muppy Doo During the Second Phase:
In this phase, Muppy Doo infiltrates your suit's operating system. Search your pause menu to find him and use Suit-O to fight back. Muppy Doo will try to mess with your Gatlian buddies and system settings. Drag the Bullet Damage slider against him, and when he falls, pull the bar towards him to knock him over. Eventually, he'll trigger a factory reset, leading to a brief game reset.

The Final Confrontation:
After the game reset, you must take extreme measures. Stab yourself in the face with Knifey while playing a clone of Donkey Kong to hit Muppy Doo. Suit-O will assist by rolling heads to stun the senator. Once you defeat Muppy Doo, the mission concludes, and you're ready for the next challenge.


What do you think about the game's decision to include a mission where you assassinate a senator? Is it a thought-provoking narrative twist or a controversial choice that crosses a moral boundary? Share your thoughts in the comments below!

Kill Senator Muppy Doo - High on Life 2 Full Walkthrough & Boss Fight Tips (2026)

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